著者：Anthony A. Mascioli and Ashley L. Park
Acute septic arthritis results from bacterial invasion of a joint space, which can occur through hematogenous spread, direct inoculation from trauma or surgery, or contiguous spread from an adjacent site of osteomyelitis or cellulitis. Despite in-depth research into the pathophysiology and treatment of acute septic arthritis, the morbidity and mortality are still significant, especially in patients at the extremes of age. The bacterial strain and the individual’s immune system determine whether a septic joint or a less severe infection develops. Even with currently available antibiotics and treatment regimens, serious complications may result. Delay in diagnosis and failure to begin treatment promptly are the most common reasons for late complications of infection.
