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Use of particulated articular cartilage for chondral defects of the knee. A, Parapatellar arthrotomy and debridement of defect. B, Sizing of defect. C, Placement of thin sheet of sterile foil in defect to create negative mold. D, Placement of particulated cartilage fragments as single layer into mold. E, Filling of mold with fibrin glue. F, Application of layer of fibrin glue to base of defect, insertion of implant, and final layer of fibrin glue to secure graft. G, For large defects, particulated cartilage can be applied directly to bed of defects (H), fixed with fibrin glue, then covered with collagen I/III membrane, which is sewn in place using standard techniques from autologous chondrocyte implantation (I).

出典

img 1:  From Ribboh JF, Cole BJ, Farr J: Particulated articular cartilage for symptomatic chondral defects of the knee, Curr Rev Musculoskelet Med 8:429, 2015.